Neurological
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Immunological
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Metabolic & Mitochondrial
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PEM
Impaired Oxygen Delivery to Muscles, Cardiac PreLoad Failure, Reduced Vo2 max, Altered Gene Expression post exertion, Hypoxia
Virals Infection, Persistence & Reactivation
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Autonomic Nervous System
Orthostatic Intolerance and Postural Orthostatic Tachycardia Syndrome, Small Fiber Neuropathy, and ANS Dysfunction
Micro-clots, Endothelial Dysfunction & Hypoxia
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Microbiome
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Mast Cells
Mast Cell Activation Syndrome and role of Mast Cells in ME
Inflammation
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Quality of Life
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Other Diseases
The overlap between ME and other diseases such as MS, Connective Tissue and Cancer
Genetics
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Overviewse & Epidemiology
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Outbreaks & History
Early research from 1950’s to 1990’s, including disease outbreaks
Structural & Mechanical Theory
The connection between cranial cervical instability (CCI), Tethered Cord, neural strain and Symptoms of ME